•Brown Seaweed Fucoidan Inhibits Cancer Progression by Dual Regulation of mir-29c/ADAM12 and miR-17-5p/PTEN Axes in Human Breast Cancer Cells
PubMed / NCBI
Fucoidan Clinical Research & Scientific Studies
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Activation of NK cells in male cancer survivors by fucoidan extracted from Cladosiphon okamuranus
PubMed / NCBI
AKT signaling is involved in fucoidan-induced inhibition of growth and migration of human bladder cancer cells
PubMed / NCBI
Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats Treated with Fucoidan
PubMed / NCBI
An Exploratory Study on the Anti-inflammatory Effects of Fucoidan in Relation to Quality of Life in Advanced Cancer Patients
PubMed / NCBI
Anti tumor activity of fucoidan in acute promyelocytic leukemia and its synergy with arsenic trioxide and ATRA
Peer-Reviewed Journal
Anti tumor activity of fucoidan in acute promyelocytic leukemia and its synergy with arsenic trioxide and ATRA in vitro and in vivo
PubMed / NCBI
Anti-Inflammatory Mechanisms of Fucoidans to Treat Inflammatory Diseases: A Review (PMC8703547)
PubMed / NCBI
Anti-tumor and anti-angiogenic effects of Fucoidan on prostate cancer: possible JAK-STAT3 pathway
PubMed / NCBI
Antiangiogenic drugs in combination with seaweed fucoidan: A mechanistic in vitro and in vivo study
PubMed / NCBI
Antiangiogenic drugs in combination with seaweed fucoidan: A mechanistic in vitro and in vivo study exploring the VEGF receptor and its downstream signaling molecules in hepatic cancer
PubMed / NCBI
Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway
PubMed / NCBI
Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway Expression
PubMed / NCBI
Anticancer properties and mechanisms of fucoidan on mouse breast cancer in vitro and in vivo
PubMed / NCBI
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3
PubMed / NCBI
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling
PubMed / NCBI
Antioxidant and anticancer properties of fucoidan isolated from Saccharina Japonica brown algae
Peer-Reviewed Journal
Antitumor activity of fucoidan against diffuse large B cell lymphoma in vitro and in vivo
PubMed / NCBI
Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling
PubMed / NCBI
Are Bioactive Molecules from Seaweeds a Novel and Challenging Option for the Prevention of HPV Infection and Cervical Cancer Therapy?—A Review
PubMed / NCBI
Are Bioactive Molecules from Seaweeds a Novel and Challenging Option for the Prevention of HPV Infection?
MDPI
Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection
PubMed / NCBI
Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies
PubMed / NCBI
Differential effects of Fucus vesiculosus fucoidan on fibroblast and macrophage cell lines inflammatory activation
ScienceDirect
Effect of Fucoidan Dietary Supplement on the Chemotherapy Treatment of Patients with Unresectable Advanced Gastric Cancer
Peer-Reviewed Journal
Effects of fucoidan supplementation on inflammatory and immune response after high-intensity exercise
Peer-Reviewed Journal
Fucoidan Alleviates Renal Fibrosis in Diabetic Kidney Disease via Inhibition of NLRP3 Inflammasome
Peer-Reviewed Journal
Fucoidan Alleviates Renal Fibrosis in Diabetic Kidney Disease via Inhibition of NLRP3 Inflammasome-Mediated Podocyte Pyroptosis
Peer-Reviewed Journal
Fucoidan alleviates the hepatorenal syndrome through inhibition organic solute transporter α/β to reduce bile acids reabsorption
ScienceDirect
Fucoidan ameliorates glucose metabolism by the improvement of intestinal barrier and inflammatory damage
ScienceDirect
Fucoidan ameliorates glucose metabolism by the improvement of intestinal barrier and inflammatory damage in type 2 diabetic rats
ScienceDirect
Fucoidan as a marine-origin prebiotic modulates the growth and antibacterial ability of Lactobacillus rhamnosus
PubMed / NCBI
Fucoidan attenuates chronic colitis and behavioral deficits by reshaping gut microbiota-brain axis balance
ScienceDirect
Fucoidan enhances the effect of chemotherapeutic drug against drug-resistant lung cancer cells
PubMed / NCBI
Fucoidan Extract Enhances the Anti-Cancer Activity of Chemotherapeutic Agents in MDA-MB-231 and MCF-7 Breast Cancer Cells
PubMed / NCBI
Fucoidan Extract Enhances the Anti-Cancer Activity of Chemotherapeutic Agents in MDA-MB-231 and MCF-7 Cells
PubMed / NCBI
Fucoidan Extracted From Cladosiphon okamuranus Tokida Induces Apoptosis of Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines
Peer-Reviewed Journal
Fucoidan Extracted From Cladosiphon okamuranus Tokida Induces Apoptosis of Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines and Primary Adult T-Cell Leukemia Cells
Peer-Reviewed Journal
Fucoidan from Fucus vesiculosus can inhibit human norovirus replication by enhancing the host innate immune response
ScienceDirect
Fucoidan from Fucus vesiculosus prevents the loss of dopaminergic neurons by alleviating mitochondrial dysfunction through targeting ATP5F1a
ScienceDirect
Fucoidan from Fucus vesiculosus suppresses hepatitis B virus replication by enhancing extracellular signal-regulated Kinase activation
PubMed / NCBI
Fucoidan from Laminaria japonica exerts antitumor effects on angiogenesis and micrometastasis in triple-negative breast cancer cells
PubMed / NCBI
Fucoidan from Lessonia trabeculata Induces Apoptosis through Caspase Dependent and Caspase-Independent Activation in 4T1 Breast Adenocarcinoma In Vitro
PubMed / NCBI
Fucoidan from marine brown algae attenuates pancreatic cancer progression by regulating p53 – NFκB crosstalk
PubMed / NCBI
Fucoidan from marine brown algae attenuates pancreatic cancer progression by regulating p53 – NFкB crosstalk
PubMed / NCBI
Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways
PubMed / NCBI
Fucoidan from Turbinaria conoides: a multifaceted ‘deliverable’ to combat pancreatic cancer progression
PubMed / NCBI
Fucoidan from Turbinaria conoides: a multifaceted deliverable to combat pancreatic cancer progression
PubMed / NCBI
Fucoidan Immobilized at the Surface of a Fibrous Mesh Presents Toxic Effects over Melanoma Cells
Peer-Reviewed Journal
Fucoidan Independently Enhances Activity in Human Immune Cells and Has a Cytostatic Effect on Prostate Cancer Cells in the Presence of Nivolumab
PubMed / NCBI
Fucoidan Independently Enhances Activity in Human Immune Cells in the Presence of Nivolumab
PubMed / NCBI
Fucoidan Induces Apoptosis and Inhibits Proliferation of Hepatocellular Carcinoma via the p38 MAPK/ERK and PI3K/Akt Signal Pathways
PubMed / NCBI
Fucoidan induces G1 arrest of the cell cycle in EJ human bladder cancer cells through down-regulation of pRB phosphorylation
ScienceDirect
Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity
PubMed / NCBI
Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway
PubMed / NCBI
Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation
PubMed / NCBI
Fucoidan Inhibition of Osteosarcoma Cells is Species and Molecular Weight Dependent
PubMed / NCBI
Fucoidan inhibits CCL22 production through NF-κB pathway in M2 macrophages
Peer-Reviewed Journal
Fucoidan inhibits CCL22 production through NF-κB pathway in M2 macrophages: a potential therapeutic strategy for cancer
Peer-Reviewed Journal
Fucoidan inhibits EGFR redistribution and potentiates sorafenib to overcome sorafenib-resistant hepatocellular carcinoma
PubMed / NCBI
Fucoidan inhibits proliferation of the SKM-1 acute myeloid leukaemia cell line via the activation of apoptotic pathways
PubMed / NCBI
Fucoidan inhibits proliferation of the SKM-1 acute myeloid leukaemia cell line via the activation of apoptotic pathways and production of reactive oxygen species
PubMed / NCBI
Fucoidan Inhibits Prostate Cancer Growth Through Modulation of Different Cell Deaths
PubMed / NCBI
Fucoidan Inhibits the Proliferation of Human Urinary Bladder Cancer T24 Cells by Blocking Cell Cycle Progression and Inducing Apoptosis
PubMed / NCBI
Fucoidan modulates gut microbiota and immunity in Peyer’s patches against inflammatory bowel disease
ScienceDirect
Fucoidan present in brown algae induces apoptosis of human colon cancer cells
Peer-Reviewed Journal
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways
Peer-Reviewed Journal
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology
Peer-Reviewed Journal
Fucoidan prevents multiple myeloma cell escape from chemotherapy-induced drug cytotoxicity
ScienceDirect
Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial Function in a Rotenone-induced Rat Model of Parkinson’s Disease
PubMed / NCBI
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress
Peer-Reviewed Journal
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats
Peer-Reviewed Journal
Fucoidan Purified from Sargassum polycystum Induces Apoptosis through Mitochondria-Mediated Pathway in HL-60 and MCF-7 Cells
PubMed / NCBI
Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer
PubMed / NCBI
Fucoidan Structure and Its Impact on Glucose Metabolism: Implications for Diabetes and Cancer Therapy
PubMed / NCBI
Fucoidan Suppresses the Growth of Human Acute Promyelocytic Leukemia Cells In Vitro and In Vivo
PubMed / NCBI
Fucoidan-Supplemented Diet Potentiates Immune Checkpoint Blockage by Enhancing Antitumor Immunity
PubMed / NCBI
Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro
PubMed / NCBI
Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro
PubMed / NCBI
Fucoidan: a promising agent for brain injury and neurodegenerative disease intervention
Peer-Reviewed Journal
Growth inhibition of pancreatic cancer by targeted delivery of gemcitabine via fucoidan-coated pH-sensitive liposomes
PubMed / NCBI
In vitro Antioxidant Properties of Fucoidan Fractions From Sargassum tenerrimum
Peer-Reviewed Journal
In vivo immunomodulatory activity of fucoidan from brown alga Undaria pinnatifida in sarcoma 180-bearing mice
ScienceDirect
Induction of Apoptosis by Fucoidan in Human Leukemia U937 Cells through Activation of p38 MAPK and Modulation of Bcl-2 Family
PubMed / NCBI
Investigation of Different Molecular Weight Fucoidan Fractions Derived from New Zealand Undaria pinnatifida in Combination with GroA Therapy in Prostate Cancer Cell Lines
PubMed / NCBI
LncRNA SELL/L-selectin promotes HPV-positive HNSCC progression and drives fucoidan-mediated therapeutic strategies
ScienceDirect
Low molecular weight fucoidan attenuates liver injury via SIRT1/AMPK/PGC1α axis in db/db mice
PubMed / NCBI
Low-molecular-weight fucoidan and high-stability fucoxanthin decrease serum alanine transaminase in patients with nonalcoholic fatty liver disease
Peer-Reviewed Journal
Natural Bioactives: Back to the Future in the Fight against Human Papillomavirus? A Narrative Review
MDPI
Natural Products as New Approaches for Treating Bladder Cancer: From Traditional Medicine to Novel Drug Discovery
MDPI
Novel fucoidan based bioactive targeted nanoparticles from Undaria pinnatifida for treatment of pancreatic cancer
PubMed / NCBI
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway
PubMed / NCBI
Protective effects of fucoidan against kidney diseases: Pharmacological insights and future perspectives
PubMed / NCBI
Sulfated fucoidan FP08S2 inhibits lung cancer cell growth in vivo by disrupting angiogenesis via targeting VEGFR2/VEGF
ScienceDirect
Sulfated fucoidan FP08S2 inhibits lung cancer cell growth in vivo by disrupting angiogenesis via targeting VEGFR2/VEGF and blocking VEGFR2/Erk/VEGF signaling
ScienceDirect
Sulfated Polysaccharide Fucoidan Ameliorates Experimental Autoimmune Myocarditis in Rats
Peer-Reviewed Journal
Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
MDPI
The Ameliorative Effects of Fucoidan in Thioacetaide-Induced Liver Injury in Mice
PubMed / NCBI
The Application of Seaweed Polysaccharides and Their Derived Products with Potential for the Treatment of Alzheimer’s Disease
MDPI
The Effect of Fucoidan, a Potential New, Natural, Anti-Neoplastic Agent on Uterine Sarcomas and Carcinosarcoma Cell Lines
PubMed / NCBI
The Effect of Fucoidan, a Potential New, Natural, Anti-Neoplastic Agent on Uterine Sarcomas and Carcinosarcoma Cell Lines: ENITEC Collaborative Study
PubMed / NCBI
The Effect of Undaria pinnatifida Fucoidan on the Pharmacokinetics of Letrozole and Tamoxifen in Patients With Breast Cancer
PubMed / NCBI
The Emerging Evidence for a Protective Role of Fucoidan from Laminaria japonica in Chronic Kidney Disease-Triggered Cognitive Dysfunction
MDPI
The Emerging Evidence for a Protective Role of Fucoidan from Laminaria japonica in CKD-Triggered Cognitive Dysfunction
MDPI
The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats
Peer-Reviewed Journal
The mechanism of fucoidan-induced apoptosis in leukemic cells: involvement of ERK1/2, JNK, glutathione, and nitric oxide
PubMed / NCBI
The natural compound fucoidan from New Zealand Undaria pinnatifida synergizes with the ERBB inhibitor lapatinib enhancing melanoma growth inhibition
PubMed / NCBI
Therapeutic Effects of Fucoidan in 6-Hydroxydopamine-Lesioned Rat Model of Parkinson’s disease: Role of NADPH oxidase-1
Peer-Reviewed Journal
Therapeutic potential of fucoidan in the reduction of hepatic pathology in murine schistosomiasis japonica
Peer-Reviewed Journal
Undaria pinnatifida Fucoidan-Rich Extract Recovers Immunity of Immunosuppressed Mice
Peer-Reviewed Journal
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